Cortisone Injection On Pimple. While both cortisone and hydrocortisone belong to the same family of corticosteroids cortisone has to be converted to hydrocortisone in the liver and wont work topically hence the injection part. Cortisone shots arent meant to completely replace your creams.

My zits dont usually take a week before they disappear. This usually works to shrink the pimple within 24 hours or. Think of a cortisone shot as an emergency treatment for a massive pimple.
The other issue is that if too much cortisone is injected into one spot or if too high a concentration of medication is used your pimple could shrink too much leaving a depression in the skin.
The fastest way to get rid of a big zit is to have your dermatologist inject it with cortisone. Cortisone shots arent meant to completely replace your creams. On the acne front you may have heard of dermatologists using cortisone injections to quickly calm large angry pimples. However in some cases the pain-relieving effect can last for much longer.